FASCINATION ABOUT NR1-SITE.COM

Using this tactic, Kalbaugh et al. assigned affinity and efficacy roles to positions inside the LBDs of the NR1 and NR2A NMDAR subunits. In situ mutation of residues in immediate contact with bound ligand affected both of those efficacy and affinity, whilst positions that stabilize the shut cleft conformation with no immediate ligand conversation c